Clopidogrel

clopidogrel

What is clopidogrel?

Clopidogrel is an antiplatelet medicine, or blood thinner. It makes your blood flow through your veins more easily. This means that your blood will be less likely to make a dangerous blood clot.

What happens if you take clopidogrel every day?

But in people at risk of heart attack or stroke, platelets can stick together inside already narrowed blood vessels to form a clot. The clot can stop blood flowing to the heart or brain and cause a heart attack or stroke. If you take it every day, clopidogrel stops platelets clumping together to form unwanted blood clots.

What is Cerner Multums clopidogrel?

Written by Cerner Multum. What is clopidogrel? Clopidogrel is used to lower your risk of having a stroke, blood clot, or serious heart problem after youve had a heart attack, severe chest pain ( angina ), or circulation problems. Clopidogrel may also be used for purposes not listed in this medication guide.

How many isomers of clopidogrel are there?

Clopidogrel is activated in the liver by cytochrome P450 enzymes, including CYP2C19. Due to opening of the thiophene ring, the chemical structure of the active metabolite has three sites that are stereochemically relevant, making a total of eight possible isomers.

What is clopidogrel used to treat?

Clopidogrel tablets are used alone or with aspirin to lower your chance of having another serious problem with your heart or blood vessels such as heart attack, stroke, or blood clot that can lead to death. Platelets are blood cells that help your blood clot normally.

What happens if you take clopidogrel every day?

But in people at risk of heart attack or stroke, platelets can stick together inside already narrowed blood vessels to form a clot. The clot can stop blood flowing to the heart or brain and cause a heart attack or stroke. If you take it every day, clopidogrel stops platelets clumping together to form unwanted blood clots.

How does clopidogrel bisulfate work?

Clopidogrel bisulfate is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. Clopidogrel prevents blood clots by irreversibly binding to the P2Y12 receptor on platelets, preventing adenosine diphosphate (ADP) from activating platelets.

What is Plavix (clopidogrel)?

Plavix is the brand name available for clopidogrel in the US. Deep vein thrombosis (DVT) is a dangerous and sometimes fatal blood clot that occurs deep within the lower leg or thigh.... What Happens After a Stroke? Signs, Symptoms, Types What is a stroke?

What is Cerner Multum?

The software solutions and databases created by Cerner Multum provide pertinent drug information, designed to allow providers to safely recommend medications with accurate dosage, while addressing interaction concerns. cross-allergy concerns.

What is clopidogrel?

Clopidogrel is an antiplatelet medicine, or blood thinner. It makes your blood flow through your veins more easily. This means that your blood will be less likely to make a dangerous blood clot.

What are the side effects of clopidogrel and aspirin?

Your doctor may prescribe clopidogrel with or instead of low-dose aspirin. The main side effect of clopidogrel is bleeding more easily than normal. You may have nosebleeds, heavier periods, bleeding gums or bruising.

How does clopidogrel affect platelets?

Clopidogrel hydrogen sulfate at recommended doses forms less of the active metabolite and so has a reduced effect on platelet activity in patients who are homozygous for nonfunctional alleles of the CYP2C19 gene, (termed “CYP2C19 poor metabolizers”). Tests are available to identify patients who are CYP2C19 poor metabolizers.

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